Liang Zhou

Liang Zhou, M.D., Ph.D.

Professor

Department: Department of Infectious Diseases & Immunology
Business Phone: (352) 294-8293
Business Email: liangzhou497@ufl.edu

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About Liang Zhou

Liang Zhou, MD, PhD, is a Professor in the Department of Infectious Diseases and Immunology (ID&I), College of Veterinary Medicine, at the University of Florida. Dr. Zhou received his MD from Nanjing Medical University (NMU), China, in 1996 and his PhD from the University of California, Los Angeles, Department of Microbiology, Immunology, and Molecular Genetics in 2004.

Dr. Zhou is a molecular immunologist with specialization in two major areas: mucosal immunity and lymphocyte development/differentiation. His research focuses on environmental impact (e.g., microbes and dietary components) on host immunity, especially in mucosal tissues. The majority of his research utilizes mouse genetic models, molecular and cellular immunological approaches, and genome-based technologies. 

In 2015, Dr. Zhou moved to the University of Florida from Northwestern University as part of UF’s Preeminence Initiative in Mucosal Immunology.

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Accomplishments

Teaching Profile

Courses Taught

  1. GMS5905 – Special Topics in Biomedical Sciences

    College of Medicine

  2. GMS7980 – Research for Doctoral Dissertation

    College of Medicine

  3. GMS7979 – Advanced Research

    College of Medicine

  4. VME7980 – Research for Doctoral Dissertation

    College of Veterinary Medicine

  5. VME4906 – Problems in Veterinary Science

    College of Veterinary Medicine

  6. VME6934 – Topics in Veterinary Medical Sciences

    College of Veterinary Medicine

  7. GMS6140 – Principles of Immunology

    College of Medicine

  8. VME6140 – VMS Graduate Journal Club: Mucosal Immunology

    College of Veterinary Medicine

  9. VME6933 – Seminar in Infectious Diseases and Experimental Pathology

    College of Veterinary Medicine

  10. VME7979 – Advanced Research

    College of Veterinary Medicine

Research Profile

Dr. Zhou is actively involved in mucosal immunology research. Over the years, he has published work in various high impact journals, including Cell, Nature, Immunity, Nature Immunology, The Journal of Experimental Medicine, Proceedings of the National Academy of Sciences (PNAS), Science Translational Medicine, and Mucosal Immunology. During the past four years, Dr. Zhou has published four papers as a corresponding author in Immunity elucidating the molecular regulation of a type of innate lymphoid cells (group 3 innate lymphoid cells—ILC3s). His papers are highly cited and have been considered landmark discoveries in the field of immunology.

As a result of his successful research, Dr. Zhou has received various prestigious awards, including being named an International Cytokine Society Young Investigator, a Cancer Research Institute Investigator, a Pew Scholar in Biomedical Sciences, and a Burroughs Wellcome Fund Investigator in the Pathogenesis of Infectious Disease. He has also been invited to give talks at numerous meetings and institutions nationally and internationally, and his work has been continuously funded by NIH and other private funding agencies since 2005.

Dr. Zhou’s research on the crosstalk between environmental factors and the host immune system in order to control bacterial infections while maintaining immune homeostasis may represent a novel target for immunologic intervention in preventing and treating infectious diseases. His research may also reveal novel therapies through modulation of Ahr activity for autoimmunity and cancer.

Areas of Interest

  • Cancer
  • Gene expression
  • Infection
  • Inflammation
  • Metabolism
  • Microbiome
  • Mucosal immunology

Publications

Academic Articles

Grants

  1. Multivalent vaccines against Clostridium difficile infection.

    Active

    Role:
    Co-Investigator
    Funding:
    UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIAID
  2. Regulation of Gut Innate Lymphoid Cells by Ahr

    Active

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NIAID
  3. Role of RORgt+ (note: g: is gamma symbol) lymphocytes in Gut Tissue Homeostasis

    Active

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NIAID
  4. Role of Bcl11b in CD4+ T cells and innate lymphoid cells

    Role:
    Co-Investigator
    Funding:
    NATL INST OF HLTH NIAID
  5. Regulation of Gut Innate Lymphoid Cells by Ahr

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NIAID
  6. ROLE OF AHR IN T LYMPHOCYTE DEVELOPMENT AND FUNCTION

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NIDDK
  7. Environmental impact on host-pathogen interaction

    Active

    Role:
    Principal Investigator
    Funding:
    BURROUGHS WELLCOME FUND
  8. a global view of the aryl hydrocarbon receptor

    Role:
    Principal Investigator
    Funding:
    PEW CHARITABLE TRUSTS SCHO PRG
  9. UF Health Cancer Center Pilot Project Grants funded through the Florida Consortium of National Cancer Institute Centers Program

    Role:
    Project Manager
    Funding:
    UF HEALTH SHANDS HOSPITAL

Education

  1. Ph.D – Microbiology, Immunology, and Molecular Genetics

    University of California, Los Angeles

  2. Medical Degree

    Nanjing Medical University

Contact Details

Phones:
Business:
(352) 294-8293
Emails:
Addresses:
Business Mailing:
PO Box 110880
GAINESVILLE FL 32611
Business Street:
PO Box 110880
GAINESVILLE FL 32611